Main Article Content
Abstract
Studies on the antioxidant activity of various plants growing in Indonesia have been widely conducted, however, information relating to testing its activity as an anti-tyrosinase and its formulation in cosmetic preparations is still limited. This literature review explores the use of plants with antioxidant and anti-tyrosinase activity and their development in cosmetic dosage forms. The method for searching references in national and international journals is carried out with the help of the Google Scholar and PubMed search engines published in the last 10 years (2014-2023). After screening by paying attention to inclusion and exclusion criteria, 32 journal articles were used to write this article. Antioxidant and anti-tyrosinase activities are found in almost all parts of the plant, which are generally extracted by maceration with ethanol solvent. Various methods for testing antioxidant activity in vitro are generally based on the presence of a redox reaction between a free radical reagent and an antioxidant which is analyzed spectrophotometrically, while testing anti-tyrosinase activity, is generally tested based on reducing the amount of dopachrome formed in the presence of anti-tyrosinase. The use of plants with antioxidant and anti-tyrosinase activity in cosmetic preparations has been carried out, although it is still limited to conventional preparations, such as creams and gels.
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References
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- Aryanti, R., Perdana, F., Syamsudin, R.A.M.R., 2021. Telaah metode pengujian aktivitas antioksidan pada teh hijau (Camellia sinensis (L.) Kuntze). J. Surya Med. 7, 15–24. https://doi.org/10.33084/jsm.v7i1.2024
- Benzie, I.F.F., Devaki, M., 2017. The ferric reducing/antioxidant power (FRAP) assay for non-enzymatic antioxidant capacity: Concepts, procedures, limitations and applications, in: Measurement of Antioxidant Activity and Capacity: Recent Trends and Applications. pp. 77–106. https://doi.org/10.1002/9781119135388.ch5
- Bose, B., Choudhury, H., Tandon, P., Kumaria, S., 2017. Studies on secondary metabolite profiling, anti-inflammatory potential, in vitro photoprotective and skin-aging related enzyme inhibitory activities of Malaxis acuminata, a threatened orchid of nutraceutical importance. J. Photochem. Photobiol. B Biol. 173, 686–695. https://doi.org/10.1016/j.jphotobiol.2017.07.010
- Cano, A., Arnao, M.B., 2018. ABTS/TEAC (2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)/Trolox®-Equivalent Antioxidant Capacity) radical scavenging mixed-mode assay. Measurement of Antioxidant Activity & Capacity, in: Measurement of Antioxidant Activity and Capacity: Recent Trends and Applications. pp. 117–139.
- Charissa, M., Djajadisastra, J., Elya, B., 2017. Uji aktivitas antioksidan dan penghambatan tirosinase serta uji manfaat gel ekstrak kulit batang taya (Nauclea subdita) terhadap kulit. J. Kefarmasian Indones. 6, 98–107.
- Chen, X., Yang, C., Jiang, G., 2021. Research progress on skin photoaging and oxidative stress. Postep. Dermatologii i Alergol. 38, 931–936. https://doi.org/10.5114/ada.2021.112275
- Dhyneu Dwi, J., Yunahara, F., Shelly, T., 2022. Aktivitas antioksidan dan inhibisi enzim tirosinase ekstrak etanol buah gandaria (Bouea macrophylla griff.) secara in vitro. Pharmacoscript 5, 63–70. https://doi.org/10.36423/pharmacoscript.v5i1.856
- Dorta, E., RodrÃguez-RodrÃguez, E.M., Jiménez-Quezada, A., Fuentes-Lemus, E., Speisky, H., Lissi, E., López-Alarcón, C., 2017. Use of the Oxygen Radical Absorbance Capacity (ORAC) Assay to Predict the Capacity of Mango (Mangifera indica L.) By-Products to Inhibit Meat Protein Oxidation. Food Anal. Methods 10, 330–338. https://doi.org/10.1007/s12161-016-0584-5
- Farage, M.A., Miller, K.W., Elsner, P., Maibach, H.I., 2008. Intrinsic and extrinsic factors in skin ageing: A review. Int. J. Cosmet. Sci. 30, 87–95. https://doi.org/10.1111/j.1468-2494.2007.00415.x
- Handoyo, D.D., Girsang, E., Nasution, A.N., Lister, I.N.E., 2021. Antioxidants and antityrosinase activity of ethanolic basil leaves extract (Ocimum americanum l.) And eugenol. Maj. Obat Tradis. 26, 84–92.
- Krutmann, J., Schikowski, T., Morita, A., Berneburg, M., 2021. Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms. J. Invest. Dermatol. 141, 1096–1103. https://doi.org/10.1016/j.jid.2020.12.011
- Mahadi, S.B., Handayani, R.A.S., Widowati, W., Wilsen, W., Dewani, Y., Fachrial, E., Lister, I.N.E., 2019. Antioxidant and anti-tyrosinase activities of Aloe vera rind and gel extracts. J. Glob. Med. Heal. Commun. 7, 170–176.
- Manosroi, J., Chankhampan, C., Kitdamrongtham, W., Zhang, J., Abe, M., Akihisa, T., Manosroi, W., Manosroi, A., 2020. In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract. Int. J. Cosmet. Sci. 42, 622–631. https://doi.org/10.1111/ics.12658
- Nur, S., Lukitaningsih, E., 2017. Skrining aktivitas antioksidan, antiaging dan penghambatan tyrosinase dari ekstrak etanolik dan etil asetat daging buah dan kulit buah langsat (Lansium domesticum corr) secara in vitro screening of antioxidants, anti-aging and tyrosinase inhibitory activi. Tradit. Med. J. 22, 63–72.
- Puspitasari, L., Dari, N.P.D.R.W., 2022. Uji Aktivitas Inhibitor Enzim Tirosinase dan Antioksidan Tagetes erecta L. sebagai Whitening Agent Formulasi Losio Pencerah Kulit. J. Mandala Pharmacon Indones. 8, 318–331. https://doi.org/10.35311/jmpi.v8i2.248
- Rachkeeree, A., Kantadoung, K., Puangpradub, R., Suksathan, R., 2020. Phytochemicals, antioxidants and anti-tyrosinase analyses of selected ginger plants. Pharmacogn. J. 12, 872–883. https://doi.org/10.5530/pj.2020.12.125
- Roohbakhsh, A., Karimi, G., Iranshahi, M., 2017. Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review. Biomed. Pharmacother. 91, 31–42. https://doi.org/10.1016/j.biopha.2017.04.057
- Sholikha, M., Febriani, A., Wahyuningrum, A., 2020. Formulasi gel ekstrak lobak (Raphanus sativus l .) sebagai antioksidan dan inhibitor tirosinase. J. Ilmu Kefarmasian 13, 15–20.
- Sinulingga, C.N., Warsidah, Sofiana, M.S.J., Safitri, I., 2022. Uji aktivitas penghambatan enzim alfa-tirosinase pada ekstrak metanol Sargassum polycystum sebagai bahan kosmetik. Oseanologia 1, 50–54.
- Siregar, I.D., Kusuma, H.S.W., Widowati, W., Marpaung, H.H., Ferdinand, S., Fachrial, E., Lister, I.N.E., 2019. Antioxidant and antityrosinase activities of ethanolic Pachyrhizuserosus peel and tuber extract. Maj. Kedokt. Bandung 51, 75–81. https://doi.org/10.15395/mkb.v51n2.1628
- Uysal, S., Zengin, G., Sinan, K.I., Ak, G., Ceylan, R., Mahomoodally, M.F., Uysal, A., Sadeer, N.B., Jekő, J., Cziáky, Z., Rodrigues, M.J., Yıldıztugay, E., Elbasan, F., Custodio, L., Uysal, S., 2021. Chemical characterization, cytotoxic, antioxidant, antimicrobial, and enzyme inhibitory effects of different extracts from one sage (Salvia ceratophyllaL.) from Turkey: open a new window on industrial purposes. RSC Adv. 11, 5295–5310. https://doi.org/10.1039/d0ra10044g
- Widayanti, A., Prastiwi, R., Wijayanti, K.T., 2021. Formulasi dan uji inhibitor tirosinase masker peel-off ekstrak etanol 96% kulit buah jeruk nipis (Citrus aurantifolia).
- Yasir, A.S., Suryaneta, S., Fahmi, A.G., Saputra, I.S., Hermawan, D., Berliyanti, R.T., 2022. Formulasi masker gel peel-off berbahan ekstrak biji kopi robusta (Coffea canephora) khas Lampung. Maj. Farmasetika 7, 153. https://doi.org/10.24198/mfarmasetika.v7i2.37312
References
Apak, R., 2017. Electron transfer-based antioxidant capacity assays and the cupric ion reducing antioxidant capacity (CUPRAC) assay. Meas. Antioxid. Act. Capacit. Recent Trends Appl. 57–75. https://doi.org/10.1002/9781119135388.ch4
Aryanti, R., Perdana, F., Syamsudin, R.A.M.R., 2021. Telaah metode pengujian aktivitas antioksidan pada teh hijau (Camellia sinensis (L.) Kuntze). J. Surya Med. 7, 15–24. https://doi.org/10.33084/jsm.v7i1.2024
Benzie, I.F.F., Devaki, M., 2017. The ferric reducing/antioxidant power (FRAP) assay for non-enzymatic antioxidant capacity: Concepts, procedures, limitations and applications, in: Measurement of Antioxidant Activity and Capacity: Recent Trends and Applications. pp. 77–106. https://doi.org/10.1002/9781119135388.ch5
Bose, B., Choudhury, H., Tandon, P., Kumaria, S., 2017. Studies on secondary metabolite profiling, anti-inflammatory potential, in vitro photoprotective and skin-aging related enzyme inhibitory activities of Malaxis acuminata, a threatened orchid of nutraceutical importance. J. Photochem. Photobiol. B Biol. 173, 686–695. https://doi.org/10.1016/j.jphotobiol.2017.07.010
Cano, A., Arnao, M.B., 2018. ABTS/TEAC (2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)/Trolox®-Equivalent Antioxidant Capacity) radical scavenging mixed-mode assay. Measurement of Antioxidant Activity & Capacity, in: Measurement of Antioxidant Activity and Capacity: Recent Trends and Applications. pp. 117–139.
Charissa, M., Djajadisastra, J., Elya, B., 2017. Uji aktivitas antioksidan dan penghambatan tirosinase serta uji manfaat gel ekstrak kulit batang taya (Nauclea subdita) terhadap kulit. J. Kefarmasian Indones. 6, 98–107.
Chen, X., Yang, C., Jiang, G., 2021. Research progress on skin photoaging and oxidative stress. Postep. Dermatologii i Alergol. 38, 931–936. https://doi.org/10.5114/ada.2021.112275
Dhyneu Dwi, J., Yunahara, F., Shelly, T., 2022. Aktivitas antioksidan dan inhibisi enzim tirosinase ekstrak etanol buah gandaria (Bouea macrophylla griff.) secara in vitro. Pharmacoscript 5, 63–70. https://doi.org/10.36423/pharmacoscript.v5i1.856
Dorta, E., RodrÃguez-RodrÃguez, E.M., Jiménez-Quezada, A., Fuentes-Lemus, E., Speisky, H., Lissi, E., López-Alarcón, C., 2017. Use of the Oxygen Radical Absorbance Capacity (ORAC) Assay to Predict the Capacity of Mango (Mangifera indica L.) By-Products to Inhibit Meat Protein Oxidation. Food Anal. Methods 10, 330–338. https://doi.org/10.1007/s12161-016-0584-5
Farage, M.A., Miller, K.W., Elsner, P., Maibach, H.I., 2008. Intrinsic and extrinsic factors in skin ageing: A review. Int. J. Cosmet. Sci. 30, 87–95. https://doi.org/10.1111/j.1468-2494.2007.00415.x
Handoyo, D.D., Girsang, E., Nasution, A.N., Lister, I.N.E., 2021. Antioxidants and antityrosinase activity of ethanolic basil leaves extract (Ocimum americanum l.) And eugenol. Maj. Obat Tradis. 26, 84–92.
Krutmann, J., Schikowski, T., Morita, A., Berneburg, M., 2021. Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms. J. Invest. Dermatol. 141, 1096–1103. https://doi.org/10.1016/j.jid.2020.12.011
Mahadi, S.B., Handayani, R.A.S., Widowati, W., Wilsen, W., Dewani, Y., Fachrial, E., Lister, I.N.E., 2019. Antioxidant and anti-tyrosinase activities of Aloe vera rind and gel extracts. J. Glob. Med. Heal. Commun. 7, 170–176.
Manosroi, J., Chankhampan, C., Kitdamrongtham, W., Zhang, J., Abe, M., Akihisa, T., Manosroi, W., Manosroi, A., 2020. In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract. Int. J. Cosmet. Sci. 42, 622–631. https://doi.org/10.1111/ics.12658
Nur, S., Lukitaningsih, E., 2017. Skrining aktivitas antioksidan, antiaging dan penghambatan tyrosinase dari ekstrak etanolik dan etil asetat daging buah dan kulit buah langsat (Lansium domesticum corr) secara in vitro screening of antioxidants, anti-aging and tyrosinase inhibitory activi. Tradit. Med. J. 22, 63–72.
Puspitasari, L., Dari, N.P.D.R.W., 2022. Uji Aktivitas Inhibitor Enzim Tirosinase dan Antioksidan Tagetes erecta L. sebagai Whitening Agent Formulasi Losio Pencerah Kulit. J. Mandala Pharmacon Indones. 8, 318–331. https://doi.org/10.35311/jmpi.v8i2.248
Rachkeeree, A., Kantadoung, K., Puangpradub, R., Suksathan, R., 2020. Phytochemicals, antioxidants and anti-tyrosinase analyses of selected ginger plants. Pharmacogn. J. 12, 872–883. https://doi.org/10.5530/pj.2020.12.125
Roohbakhsh, A., Karimi, G., Iranshahi, M., 2017. Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review. Biomed. Pharmacother. 91, 31–42. https://doi.org/10.1016/j.biopha.2017.04.057
Sholikha, M., Febriani, A., Wahyuningrum, A., 2020. Formulasi gel ekstrak lobak (Raphanus sativus l .) sebagai antioksidan dan inhibitor tirosinase. J. Ilmu Kefarmasian 13, 15–20.
Sinulingga, C.N., Warsidah, Sofiana, M.S.J., Safitri, I., 2022. Uji aktivitas penghambatan enzim alfa-tirosinase pada ekstrak metanol Sargassum polycystum sebagai bahan kosmetik. Oseanologia 1, 50–54.
Siregar, I.D., Kusuma, H.S.W., Widowati, W., Marpaung, H.H., Ferdinand, S., Fachrial, E., Lister, I.N.E., 2019. Antioxidant and antityrosinase activities of ethanolic Pachyrhizuserosus peel and tuber extract. Maj. Kedokt. Bandung 51, 75–81. https://doi.org/10.15395/mkb.v51n2.1628
Uysal, S., Zengin, G., Sinan, K.I., Ak, G., Ceylan, R., Mahomoodally, M.F., Uysal, A., Sadeer, N.B., Jekő, J., Cziáky, Z., Rodrigues, M.J., Yıldıztugay, E., Elbasan, F., Custodio, L., Uysal, S., 2021. Chemical characterization, cytotoxic, antioxidant, antimicrobial, and enzyme inhibitory effects of different extracts from one sage (Salvia ceratophyllaL.) from Turkey: open a new window on industrial purposes. RSC Adv. 11, 5295–5310. https://doi.org/10.1039/d0ra10044g
Widayanti, A., Prastiwi, R., Wijayanti, K.T., 2021. Formulasi dan uji inhibitor tirosinase masker peel-off ekstrak etanol 96% kulit buah jeruk nipis (Citrus aurantifolia).
Yasir, A.S., Suryaneta, S., Fahmi, A.G., Saputra, I.S., Hermawan, D., Berliyanti, R.T., 2022. Formulasi masker gel peel-off berbahan ekstrak biji kopi robusta (Coffea canephora) khas Lampung. Maj. Farmasetika 7, 153. https://doi.org/10.24198/mfarmasetika.v7i2.37312