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Abstract
ABSTRACT
The absorbtion-based ointment of ethanolic extract of binahong leaves (Anredera cordifolia
(Ten.) Steenis) on 10% concentrate has antibacterial activity towards Staphylococcus aureus. In order to
improve the activity of this ethanolic extract of binahong leaves, it is necessarily to adjust the ointment’s
base of formulation. The aims of study are to determine the ointment’s physical characteristics which
various base such as hydrocarbon, absorbtion and water solubility.
The ethanolic extract of binahong leaves obtained from maceration method, using 70% of
ethanol. The ointment was made based on the variation of its base which are hydrocarbon, absorbtion and
water solubility. The obtained oinment then was examined on its physical characteristics properties
including organoleptic test, pH, viscosity, stickiness, spreadability, and antibacterial activity toward
Staphylococcus aureus on the agar plate medium. The organoleptic and pH test result data were analyzed
descriptively. The data of stickiness, viscosity were analyzed using one-way ANOVA and Tukey with the
level of confidence up to 95%, whilst the spreadability data was analyzed using Kruskal wallis and Man
whitney.
There were significant differences between the results of viscosity, stickiness, on each formula
of ethanolic extract ointment of binahong leaves. However, there were no significant differences on the
pshycal characteristic of the pH, organoleptic, homogenic, and spreadability. Â
Keywords: Ointment, Binahong leaves, Antibacterial activity, Staphylococcus aureus.
The absorbtion-based ointment of ethanolic extract of binahong leaves (Anredera cordifolia
(Ten.) Steenis) on 10% concentrate has antibacterial activity towards Staphylococcus aureus. In order to
improve the activity of this ethanolic extract of binahong leaves, it is necessarily to adjust the ointment’s
base of formulation. The aims of study are to determine the ointment’s physical characteristics which
various base such as hydrocarbon, absorbtion and water solubility.
The ethanolic extract of binahong leaves obtained from maceration method, using 70% of
ethanol. The ointment was made based on the variation of its base which are hydrocarbon, absorbtion and
water solubility. The obtained oinment then was examined on its physical characteristics properties
including organoleptic test, pH, viscosity, stickiness, spreadability, and antibacterial activity toward
Staphylococcus aureus on the agar plate medium. The organoleptic and pH test result data were analyzed
descriptively. The data of stickiness, viscosity were analyzed using one-way ANOVA and Tukey with the
level of confidence up to 95%, whilst the spreadability data was analyzed using Kruskal wallis and Man
whitney.
There were significant differences between the results of viscosity, stickiness, on each formula
of ethanolic extract ointment of binahong leaves. However, there were no significant differences on the
pshycal characteristic of the pH, organoleptic, homogenic, and spreadability. Â
Keywords: Ointment, Binahong leaves, Antibacterial activity, Staphylococcus aureus.