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Abstract

ABSTRACT
Sodium Carboxymethyl  Cellulose (CMC Na) commonly used as  binder  on toothpaste
becauseits has good viscosity. The active ingredient of two type of toothpaste is ethanol extract of
guava leaves (EEDJB) and ethanol extract of red betel leaf (EEDSM), respectively which has the
potential for antiplaque on teeth. The purpose of this study to determine the effect of variations
concentration of CMC Naagainst  physical characteristics  from  toothpaste EEDJB and EEDSM.
EEDJB and EEDSM  had made by maceration method  using ethanol 70%  as a solvent. Three
different concentrations of CMC Naof  toothpaste formulation EEDJB are FI (0.5%); FII (0.75%);
FIII (1.00%) and EEDSM are FI (0.45%); FII (0.67%); FIII (0.90%). Toothpaste of EEDSM and
EEDJB  had  tested against its physical characteristics. Based on theexperimental results of
toothpaste formulations EEDJB and EEDSM states that the higher concentration of CMC  Na
hadn’t affect the organoleptic and foaming test, but the viscosity becomes higher and  the potency
dispersive of becomes  decreases. Value  of  viscosity (dPas) toothpaste EEDJB for FI (123,33 ±
5,77); FII (256,67 ± 20,81); FIII (283,33 ± 10,40), while  toothpaste EEDSM for FI (125±5); FII
(250±25); FIII (316,6± 28,87. The average of the potency dispersive  (cm2) of  toothpaste EEDJB
with a load of 150 grams for F1 (1,75); F2 (1,21); F3 (0,89), while toothpaste EEDSM with a load
of 150 grams for F1 (1,64); F2 (1,26); F3 (0,73).
Keywords :    CMC Na, ethanolic extract of guajava leaves, ethanolic extract of red betle
leaves, toothpaste

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