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July 23, 2021
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July 23, 2021
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Abstract

ABSTRACT Breast cancer is the most common cancer found in women and is the dominant cancer in Indonesia. Cancer treatments such as chemotherapy can affect the quality of life of patients including physical, psychological, and social. The purpose of this study is to measure the quality of life of breast cancer patients. This research used cross sectional study design. The patient quality of life was measured using the EORTC QLQ-C30 questionnaire. The subjects of this study were breast cancer patients in RSUP Dr. Kariadi Semarang meeting the inclusion criteria. The cognitive function domain, social function, emotional function, role function, and physical function were 86,15 ± 17,82; 84,10 ± 21,13; 82,56 ± 17,72; 77,95 ± 29,77; 76,72 ± 22,95, respectively. Whereas in symptom scale group from pain, fatigue, insomnia, appetite loss, financial difficulties, nausea and vomiting, constipation, dyspnea and diarrhea were 32,82 ± 30,33; 32,65 ± 21,14; 31,79 ± 34,58; 31,79 ± 32,51; 30,77 ± 32,44; 23,59 ± 25,67; 17,95 ± 30,9; 4,62 ± 14,28; 4,10 ± 13,83, respectively. For global health status / quality of life obtained 72.18 ± 18.94. The highest score on the functional scale is the cognitive function domain and the lowest score is the physical function.On the scale of symptom the domain that has the highest score is the pain domain and the lowest score is the diarrhea domain. Keywords: quality of life, breast cancer, EORTC QLQ-C30

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References

  1. Afifah, V. A. dan Sarwoko., 2020, Faktor-faktor yang mempengaruhi Kualitas Hidup Pasien Kanker Payudara yang Menjalani Kemoterapi, Jurnal Komunikasi Kesehatan, 10 (1), 29–37.
  2. Andersen, K. G., Jensen, M. B., Kehlet, H., Gärtner, R., Eckhoff, L., dan Kroman, N., 2012, Persistent pain, sensory disturbances and functional impairment after adjuvant chemotherapy for breast cancer: Cyclophosphamide, epirubicin and fluorouracil compared with ocetaxel
  3. epirubicin and cyclophosphamide, Acta Oncologica, 51 (8), 1036–044.
  4. Boltong, A., Aranda, S., Keast, R., Wynne, R., Francis, P. A., Chirgwin, J., dan Gough, K., 2014, A prospective cohort study of the effects of adjuvant breast cancer chemotherapy on taste function, food liking, appetite and associated nutritional outcomes, PLoS ONE, 9 (7), 1–9.
  5. Bower, J. E., 2014, Cancer-related fatigue--mechanisms, risk factors, and treatments., Nature reviews. Clinical oncology, 11 (10), 597–609.
  6. Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., dan Jemal, A., 2018, Global Cancer Statistics 2018 : GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries, CA: A Cancer Journal for Clinician, 394–424.
  7. Chean, D. C., Zang, W. K., Lim, M., dan Zulkefle, N., 2016, Health Related Quality of Life (HRQoL) among breast cancer patients receiving chemotherapy in hospital Melaka: Single centre experience, Asian Pacific Journal of Cancer Prevention, 17 (12), 6021–6026.
  8. Chen, Q., Li, S., Wang, M., Liu, L., dan Chen, G., 2018, Health-Related Quality of Life among Women Breast Cancer Patients in Eastern China, BioMed Research International, 2018. Costa, A. R., Fontes, F., Pereira, S., Gonçalves, M., Azevedo, A., dan Lunet, N., 2014, Impact of breast cancer treatments on sleep disturbances - A systematic review, Breast, 23 (6), 697–709.
  9. Costa, W. A., Monteiro, M. N., Queiroz, J. F., dan Gonçalves, A. K., 2017, Pain and quality of life in breast cancer patients, Clinics, 72 (12), 758–763.
  10. Fayer, P., Aaronson, N. K., Bjordal, K., Groenvold, M., Curran, D., dan Bottomley, A., 2001, The EORTC QLQ-C30 Scoring Manual 3rd Edition, European Organisation for Research and Treatment of Cancer.
  11. Haidari, R. El, Abbas, L. A., Nerich, V., dan Anota, A., 2020, Factors associated with healthrelated quality of life in women with breast cancer in the middle east: A systematic review, Cancers MDPI, 12 (3), 1–19.
  12. Hassen, A. M., Taye, G., Gizaw, M., dan Hussien, F. M., 2019, Quality of life and associated factors among patients with breast cancer under chemotherapy at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia, PLoS ONE, 14 (9), 1–13.
  13. Juwita, D. A., Almahdy, dan Afdila, R., 2018, Pengaruh Karatkeristik Pasien Terhadap Kualitas Hidup Terkait Kesehatan Pada Pasien Kanker Payudara di RSUP Dr.M. Djamil Padang, Indonesia, Jurnal Sains Farmasi & Klinis, 5 (2), 126–133.
  14. Kecke, S., Ernst, J., Einenkel, J., Singer, S., dan Hinz, A., 2017, Psychometric Properties of the Fatigue Questionnaire EORTC QLQ-FA12 in a Sample of Female Cancer Patients, Journal of Pain and Symptom Management, 54 (6), 922–928.
  15. Kemenkes RI, 2016, InfoDatin Bulan Peduli Kanker Payudara, Kementrian Kesehatan Republik Indonesia.
  16. Kim, S. H., Jo, M., Kim, H., dan Ahn, J., 2012, Mapping EORTC QLQ-C30 onto EQ-5D for the assessment of cancer patients, Health and Quality of Life Outcomes, 1–6.
  17. Meraner, V., Gamper, E. M., Grahmann, A., Giesinger, J. M., Wiesbauer, P., Sztankay, M., Zeimet, A. G., Sperner-Unterweger, B., dan Holzner, B., 2012, Monitoring physical and psychosocial symptom trajectories in ovarian cancer patients receiving chemotherapy, BMC Cancer, 12.
  18. Pergolotti, M., Deal, A. M., Williams, G. R., Bryant, A. L., Bensen, J. T., Muss, H. B., dan Reeve, B. B., 2017, Activities, function, and health-related quality of life (HRQOL) of older adults with cancer, Journal of Geriatric Oncology, 8 (4), 249–254.
  19. Perwitasari, D. A., Atthobari, J., Dwiprahasto, I., Hakimi, M., Melderblom, H., Putter, H., Nortier, J. W. R., Guchelaar, H., dan Kaptein, A. A., 2011, Translation and Validation of EORTC
  20. QLQ-C30 into Indonesian Version for Cancer Patients in Indonesia, Japanese Journal of Clinical Oncology, 41 (January), 519–529.
  21. Sanford, S. D., Wagner, L. I., Beaumont, J. L., Butt, Z., Sweet, J. J., dan Cella, D., 2013, Longitudinal prospective assessment of sleep quality: Before, during, and after adjuvant chemotherapy for breast cancer, Supportive Care in Cancer, 21 (4), 959–967.
  22. Shafaie, F. S., Mirghadourvand, M., dan Amirzehni, J., 2019, Effect of Aerobic Exercise on Cancer-related Fatigue, Indian Journal of Palliative Care, 25 (1), 73–8.
  23. Shin, W. kyoung, Song, S., Jung, S. Y., Lee, E., Kim, Z., Moon, H. G., Noh, D. Y., dan Lee, J. E., 2017, The association between physical activity and health-related quality of life among breast cancer survivors, Health and Quality of Life Outcomes, 15 (1), 1–9.
  24. Du Toit, G. C. dan Kidd, M., 2015, Prospective Quality of Life Study of South African Women Undergoing Treatment for Advanced-stage Cervical Cancer, Clinical Therapeutics, 37 (10), 2324–2331.
  25. Tunas, I. K., Yowani, S. C., Indrayathi, P. A., Noviyani, R., dan Budiana, I. N. G., 2016, The Assessment Quality of Life For Patients with Cervical Cancer Using Chemotherapy Paclitaxel-Carboplatin in Sanglah, Indonesian Journal of Clinical Pharmacy, 5 (1), 35–46.
  26. Wan Puteh, S. E., Siwar, C., Zaidi, M. A. S., dan Abdul Kadir, H., 2019, Health related quality of life (HRQOL) among low socioeconomic population in Malaysia, BMC Public Health, 19 (Suppl 4), 4–11.