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Abstract
ABSTRACT
Betle leaves has been used as antibacteria or antiseptic and was formulated in gargle. Betel leaves extract
formulated in ointment in order to practical and effective to the skin. The aim of this research is to know the influence
of difference concentration of betle leaves extract in ointment to its physical properties and antibacteria effet againts
Staphylococcus aureus.
Extract was obtained from leaves of the plant by decoction and continued by extraction with ether. Ointment
were made in fine formulas with extract concentration 0.2, 0.4, 0.6, 0.8 and 1% w/w. The ointment was tested for its
physical properties such as consisted of homogenity, viscosity, stickness and spreadibility. Antibacterial activity
againts Staphylococcus aureus was tested by diffusion method.
The result of this research shown that the ointment homogenous. The difference of extract concentration had not
influence on their viscosity and dispersive power, however had influence on their fixed time. The ointment of betle
leaves extract had antibacterial activity againts Staphylococcus aureus.
Keywords: Betle leaves extract, Ointment, Physical Test, antibacteri