POTENSI PRODUKSI ANDROGRAPHOLIDE DARI SAMBILOTO (Andrographis paniculata Nees) MELALUI PROSES EKSTRAKSI HIDROTROPI

Authors

  • R.D Ratnani Program Studi Teknik Kimia Fakultas Teknik Universitas Wahid Hasyim Semarang Jalan Menoreh Tengah X no 22 Sampangan Semarang
  • I Hartati Program Studi Teknik Kimia Fakultas Teknik Universitas Wahid Hasyim Semarang Jalan Menoreh Tengah X no 22 Sampangan Semarang
  • L. Kurniasari Program Studi Teknik Kimia Fakultas Teknik Universitas Wahid Hasyim Semarang Jalan Menoreh Tengah X no 22 Sampangan Semarang

DOI:

https://doi.org/10.36499/jim.v8i1.279

Abstract

Andrographolide merupakan senyawa fitokimia yang memiliki berbagai
fungsi kesehatan. Salah satunya, andrographolide memiliki sifat sebagai anti
malaria. Andrographolide dapat dengan mudah larut dalam methanol, ethanol,
pyridine, asam asetat, dan aceton, tetapi sedikit larut dalam ether dan air.
Ekstraksi andrographolide yang telah banyak diterapkan adalah ekstraksi
menggunakan alkohol. Proses tersebut menyebabkan terjadinya degradasi
andrographolide. Larutan hidrotrop dapat meningkatkan kelarutan senyawa
yang tidak larut dalam air. Ekstraksi andrographolide menggunakan larutan
hidrotrop dapat diterapkan karena andrographolide merupakan senyawa yang
tidak larut dalam air. Ekstraksi andrographolide menggunakan larutan
hidrotrop berupa larutan sodium salisilat dan sodium asetat mampu
menghasilkan ekstrak dengan berat masing-masing 0,57 g dan 0,18 g.
Kata Kunci: andrographolide, hidrotop, ekstraksi, sambilotio

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Published

2012-04-20

Issue

Vol. 8 No. 1 (2012)

Section

Articles

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