PREDIKSI KELARUTAN THEOBROMINE PADA BERBAGAI PELARUT MENGGUNAKAN PARAMETER KELARUTAN HILDEBRAND
DOI:
https://doi.org/10.36499/jim.v8i1.280Abstract
Indonesia sebagai penghasil kakao ketiga terbesar ketiga diduniaberpotensi menghasilkan limbah berupa kulit biji buah kakao. Kulit biji buah
kakao mengandung protein yang dapat dimanfaatkan sebagai pakan ternak serta
theobromine yang dapat digunakan sebagai produk farmasi. Theobromine dari
kulit biji buah kakao dapat dipisahkan melalui proses ekstraksi. Salah satu
faktor yang mempengaruhi proses ekstraksi adalah jenis pelarut. Pemilihan
pelarut pada proses ekstraksi dapat dilakukan berdasarkan prediksi kelarutan
solut menggunakan parameter kelarutan Hildebrand. Nilai parameter kelarutan
Hildebrand theobromine adalah 20,977 MPa1/2. Pelarut yang memiliki deviasi
nilai parameter kelarutan Hildebrand yang kecil adalah metilen klorida dan
aceton sehingga dapat diartikan bahwa theobromine mudah larut dalam metilen
klorida dan aceton.
Kata Kunci: theobromine, parameter kelarutan Hildebrand
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